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2010.10.22 - Jon Newman - Shaping the organization of large cortical networks with controlled sensory environments

  • Examine emergent network properties.
  • The leading edge of the burst is very sharp
  • Bursts may be associated with extreme polarization, limited only by the refractory period
  • Synaptically blocked networks appear to be "decodable", while the bursts appear to destroy predictability of response
  • Network signal impedance
    • Wants a measure of connectivity
    • Path length (encoding distance)
  • How does shortening the delay associate with unstable network behavior?
  • Continuous stimulation over the development of the network in hopes of removing "bursting" and training the culture with relevant information.